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Optical Tissue Clearing to Study the Intra-Pulmonary Biodistribution of Intravenously Delivered Mesenchymal Stromal Cells and Their Interactions with Host Lung Cells

Mesenchymal stromal cells (MSCs) injected intravenously are trapped in the capillaries of the lungs and die within the first 24 h. Studying the biodistribution and fate of labelled therapeutic cells in the 3D pulmonary context is important to understand their function in this organ and gain insights...

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Detalles Bibliográficos
Autores principales: Pichardo, Alejandra Hernandez, Amadeo, Francesco, Wilm, Bettina, Lévy, Raphaël, Ressel, Lorenzo, Murray, Patricia, Sée, Violaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699424/
https://www.ncbi.nlm.nih.gov/pubmed/36430651
http://dx.doi.org/10.3390/ijms232214171