1,25(OH)(2)D(3) Promotes Macrophage Efferocytosis Partly by Upregulating ASAP2 Transcription via the VDR-Bound Enhancer Region and ASAP2 May Affect Antiviral Immunity

The active form of vitamin D(3), i.e., 1,25(OH)(2)D(3), exerts an anti-inflammatory effect on the immune system, especially macrophage-mediated innate immunity. In a previous study, we identified 1,25(OH)(2)D(3)-responsive and vitamin D receptor (VDR)-bound super-enhancer regions in THP-1 cells. Her...

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Detalles Bibliográficos
Autores principales: Shi, Hui, Duan, Jiangling, Wang, Jiayu, Li, Haohao, Wu, Zhiheng, Wang, Shuaideng, Wu, Xueyan, Lu, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699620/
https://www.ncbi.nlm.nih.gov/pubmed/36432619
http://dx.doi.org/10.3390/nu14224935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699620/
https://www.ncbi.nlm.nih.gov/pubmed/36432619
http://dx.doi.org/10.3390/nu14224935

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