MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium

Secreted mucus is a frontline defense against respiratory infection, enabling the capture and swift removal of infectious or irritating agents from the lungs. Airway mucus is composed of two mucins: mucin 5B (MUC5B) and 5AC (MUC5AC). Together, they form a hydrogel that can be actively transported by...

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Detalles Bibliográficos
Autores principales: Song, Daniel, Iverson, Ethan, Kaler, Logan, Boboltz, Allison, Scull, Margaret A., Duncan, Gregg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699686/
https://www.ncbi.nlm.nih.gov/pubmed/36427316
http://dx.doi.org/10.1126/sciadv.abq5049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699686/
https://www.ncbi.nlm.nih.gov/pubmed/36427316
http://dx.doi.org/10.1126/sciadv.abq5049

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