Cell-intrinsic ceramides determine T cell function during melanoma progression

Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac. Ceramide generates ceramide-enriched platforms that are involved in receptor clustering within cellular membrane...

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Detalles Bibliográficos
Autores principales: Hose, Matthias, Günther, Anne, Naser, Eyad, Schumacher, Fabian, Schönberger, Tina, Falkenstein, Julia, Papadamakis, Athanasios, Kleuser, Burkhard, Becker, Katrin Anne, Gulbins, Erich, Haimovitz-Friedman, Adriana, Buer, Jan, Westendorf, Astrid M, Hansen, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699697/
https://www.ncbi.nlm.nih.gov/pubmed/36426850
http://dx.doi.org/10.7554/eLife.83073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699697/
https://www.ncbi.nlm.nih.gov/pubmed/36426850
http://dx.doi.org/10.7554/eLife.83073

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