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Cascade-Enhanced Catalytic Nanocomposite with Glutathione Depletion and Respiration Inhibition for Effective Starving-Chemodynamic Therapy Against Hypoxic Tumor

BACKGROUND: Although chemodynamic therapy (CDT) has attracted enormous attention in anti-tumor studies for converting endogenous hydrogen peroxide (H(2)O(2)) into toxic hydroxyl radicals (•OH) by Fenton-type reaction, the treating effects of using CDT alone is still unsatisfying. Recently, glucose o...

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Detalles Bibliográficos
Autores principales: Zhang, Yiran, Hu, Hongzhi, Deng, Xiangtian, Song, Qingcheng, Xing, Xin, Liu, Weijian, Zhang, Yingze
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699701/
https://www.ncbi.nlm.nih.gov/pubmed/36438608
http://dx.doi.org/10.2147/IJN.S382750