Hypoxia Enhances Glioma Resistance to Sulfasalazine-Induced Ferroptosis by Upregulating SLC7A11 via PI3K/AKT/HIF-1α Axis

Glioma is the most common primary brain tumor, with a high rate of recurrence and treatment resistance. Glioblastoma is highly invasive, infiltrating surrounding brain parenchyma, and is known to cause intracranial metastasis resulting in a dismal prognosis. Hypoxia contributes significantly to chem...

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Detalles Bibliográficos
Autores principales: Sun, Shicheng, Guo, Changfa, Gao, Taihong, Ma, Dengzhen, Su, Xiangsheng, Pang, Qi, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699746/
https://www.ncbi.nlm.nih.gov/pubmed/36439690
http://dx.doi.org/10.1155/2022/7862430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699746/
https://www.ncbi.nlm.nih.gov/pubmed/36439690
http://dx.doi.org/10.1155/2022/7862430

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