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The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability

Cyclin F, unlike canonical and transcriptional cyclins, does not bind or activate any cyclin-dependent kinases. Instead, it harbors an F-box motif and primarily functions as the substrate recognition subunit of the Skp1-Cul1-F-box E3 ubiquitin ligase complex, SCF(Cyclin) (F). By targeting specific p...

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Detalles Bibliográficos
Autores principales: Sharma, Savitha S., Pledger, W. Jack, Kondaiah, Paturu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699750/
https://www.ncbi.nlm.nih.gov/pubmed/36342772
http://dx.doi.org/10.18632/aging.204372