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The deubiquitylase USP7 is a novel cyclin F-interacting protein and regulates cyclin F protein stability
Cyclin F, unlike canonical and transcriptional cyclins, does not bind or activate any cyclin-dependent kinases. Instead, it harbors an F-box motif and primarily functions as the substrate recognition subunit of the Skp1-Cul1-F-box E3 ubiquitin ligase complex, SCF(Cyclin) (F). By targeting specific p...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699750/ https://www.ncbi.nlm.nih.gov/pubmed/36342772 http://dx.doi.org/10.18632/aging.204372 |