IGF1 gene therapy in middle-aged female rats delays reproductive senescence through its effects on hypothalamic GnRH and kisspeptin neurons

The process of aging is the result of progressive loss of homeostasis and functional body impairment, including the central nervous system, where the hypothalamus plays a key role in regulating aging mechanisms. The consequences of aging include a chronic proinflammatory environment in the hypothala...

Descripción completa

Detalles Bibliográficos
Autores principales: Dolcetti, Franco Juan Cruz, Falomir-Lockhart, Eugenia, Acuña, Francisco, Herrera, Macarena Lorena, Cervellini, Sofia, Barbeito, Claudio Gustavo, Grassi, Daniela, Arevalo, Maria-Angeles, Bellini, María José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699762/
https://www.ncbi.nlm.nih.gov/pubmed/36326686
http://dx.doi.org/10.18632/aging.204360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699762/
https://www.ncbi.nlm.nih.gov/pubmed/36326686
http://dx.doi.org/10.18632/aging.204360

Ejemplares similares