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ESR1 dysfunction triggers neuroinflammation as a critical upstream causative factor of the Alzheimer’s disease process
Alzheimer's disease (AD) accounts for approximately 60% of dementia cases worldwide. Advanced age is the most significant risk factor for AD and approximately two-thirds of cases relate to women. While the previous meta-analysis suggests that estrogen receptor (ESR) genetic polymorphisms are cl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699767/ https://www.ncbi.nlm.nih.gov/pubmed/36326669 http://dx.doi.org/10.18632/aging.204359 |