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Spike Protein Subunits of SARS-CoV-2 Alter Mitochondrial Metabolism in Human Pulmonary Microvascular Endothelial Cells: Involvement of Factor Xa

BACKGROUND: Mitochondria have been involved in host defense upon viral infections. Factor Xa (FXa), a coagulating factor, may also have influence on mitochondrial functionalities. The aim was to analyze if in human pulmonary microvascular endothelial cells (HPMEC), the SARS-CoV-2 (COVID-19) spike pr...

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Detalles Bibliográficos
Autores principales: Zekri-Nechar, Khaoula, Zamorano-León, José J., Reche, Carmen, Giner, Manel, López-de-Andrés, Ana, Jiménez-García, Rodrigo, López-Farré, Antonio J., Martínez-Martínez, Carlos Hugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699787/
https://www.ncbi.nlm.nih.gov/pubmed/36438904
http://dx.doi.org/10.1155/2022/1118195