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Isoflavone daidzein ameliorates renal dysfunction and fibrosis in a postmenopausal rat model: Intermediation of angiotensin AT1 and Mas receptors and microRNAs 33a and 27a

OBJECTIVE(S): Chronic kidney disease (CKD), accompanied by renal dysfunction, fibrosis, and apoptosis, is highly prevalent in postmenopausal women. We tested the hypothesis that isoflavone daidzein may ameliorate renal dysfunction and fibrosis through angiotensin II type 1 (AT1R) and angiotensin 1-7...

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Detalles Bibliográficos
Autores principales: Askaripour, Majid, Najafipour, Hamid, Saberi, Shadan, Yazdani, Saleh, Jafarinejad-Farsangi, Saeideh, Rajabi, Soodeh, Jafari, Elham, Proost, Paul, Struyf, Sofie, Poosti, Fariba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699944/
https://www.ncbi.nlm.nih.gov/pubmed/36474573
http://dx.doi.org/10.22038/IJBMS.2022.66572.14609