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PPD in HBsAg vaccine formulation suppressed IFN-γ and IL-4 cytokine responses and induced long-lived humoral immune responses: Results from 220-day monitoring of specific IgG responses

OBJECTIVE(S): Here, immune responses and long-lived IgG responses of HBsAg-Alum, HBsAg-MF59, as well as HBsAg-MF59 were compared when formulated with PPD.  MATERIALS AND METHODS: BALB/c mice were vaccinated subcutaneously three times with a two-week -interval. Then, specific IgG, long-lived IgG resp...

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Detalles Bibliográficos
Autores principales: Mirzaee, Rayhaneh, Nemati, Fahimeh, Mirzaee, Mina, Golkaran, Bahareh, Khorasani, Akbar, Rashedi, Niloufar, Asgarhalvaei, Fatemeh, Savoji, Mohammad Ali, Mahdavi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699948/
https://www.ncbi.nlm.nih.gov/pubmed/36474577
http://dx.doi.org/10.22038/IJBMS.2022.61941.13710