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Crocin attenuates endoplasmic reticulum stress in methylglyoxal-induced diabetic nephropathy in male mice: MicroRNAs alterations and glyoxalase 1-Nrf2 signaling pathways

OBJECTIVE(S): Accumulation of methylglyoxal (MGO) occurs in diabetes. MicroRNA-204 is an important intracellular marker in the diagnosis of endoplasmic reticulum stress. Crocin (Crn) has beneficial effects for diabetes, but the effect of Crn on MGO-induced diabetic nephropathy has not been investiga...

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Detalles Bibliográficos
Autores principales: Radmehr, Vahid, Ahangarpour, Akram, Mard, Seyyed Ali, Khorsandi, Layasadat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699949/
https://www.ncbi.nlm.nih.gov/pubmed/36474578
http://dx.doi.org/10.22038/IJBMS.2022.65824.14479