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TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis

OBJECTIVE(S): Acute kidney injury (AKI) is a major component of isoproterenol (ISO) induced cardiorenal syndrome. In this study, we investigated the effect of TLR4‐IN‐C34 as a toll-like receptor (TLR)-4 inhibitor on ameliorating ISO-induced AKI and the possible molecular underlying pathways. MATERIA...

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Detalles Bibliográficos
Autores principales: Abdelsalam, Hadeer M., Helal, Manar G., Abu-Elsaad, Nashwa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699956/
https://www.ncbi.nlm.nih.gov/pubmed/36474570
http://dx.doi.org/10.22038/IJBMS.2022.67168.14727