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TLR4‐IN‐C34 protects against acute kidney injury via modulating TLR4/MyD88/NF-κb axis, MAPK, and apoptosis
OBJECTIVE(S): Acute kidney injury (AKI) is a major component of isoproterenol (ISO) induced cardiorenal syndrome. In this study, we investigated the effect of TLR4‐IN‐C34 as a toll-like receptor (TLR)-4 inhibitor on ameliorating ISO-induced AKI and the possible molecular underlying pathways. MATERIA...
Autores principales: | Abdelsalam, Hadeer M., Helal, Manar G., Abu-Elsaad, Nashwa M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9699956/ https://www.ncbi.nlm.nih.gov/pubmed/36474570 http://dx.doi.org/10.22038/IJBMS.2022.67168.14727 |
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