Cargando…

GILoop: Robust chromatin loop calling across multiple sequencing depths on Hi-C data

Graph and image are two common representations of Hi-C cis-contact maps. Existing computational tools have only adopted Hi-C data modeled as unitary data structures but neglected the potential advantages of synergizing the information of different views. Here we propose GILoop, a dual-branch neural...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Fuzhou, Gao, Tingxiao, Lin, Jiecong, Zheng, Zetian, Huang, Lei, Toseef, Muhammad, Li, Xiangtao, Wong, Ka-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700007/
https://www.ncbi.nlm.nih.gov/pubmed/36444296
http://dx.doi.org/10.1016/j.isci.2022.105535