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Chromodomain helicase DNA-binding domain 2 maintains spermatogonial self-renewal by promoting chromatin accessibility and mRNA stability

Chromodomain helicase DNA-binding domain 2 (CHD2) is a chromatin remodeling factor involved in many developmental processes. However, its role in male germ cell development has not been elucidated. Here, we confirm that CHD2 expression is enriched in the male germline. In a heterozygous knockout mou...

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Detalles Bibliográficos
Autores principales: Min, Ziqian, Xin, Huan, Liu, Xiaowen, Wan, Jingyu, Fan, Ziling, Rao, Xinxu, Fan, Jiahui, Yang, Lifang, Li, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700024/
https://www.ncbi.nlm.nih.gov/pubmed/36444304
http://dx.doi.org/10.1016/j.isci.2022.105552