Siponimod exerts neuroprotective effects on the retina and higher visual pathway through neuronal S1PR1 in experimental glaucoma

Sphingosine-1-phosphate receptor (S1PR) signaling regulates diverse pathophysiological processes in the central nervous system. The role of S1PR signaling in neurodegenerative conditions is still largely unidentified. Siponimod is a specific modulator of S1P1 and S1P5 receptors, an immunosuppressant...

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Detalles Bibliográficos
Autores principales: Basavarajappa, Devaraj, Gupta, Vivek, Chitranshi, Nitin, Wall, Roshana Vander, Rajput, Rashi, Pushpitha, Kanishka, Sharma, Samridhi, Mirzaei, Mehdi, Klistorner, Alexander, Graham, Stuart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700103/
https://www.ncbi.nlm.nih.gov/pubmed/36204852
http://dx.doi.org/10.4103/1673-5374.344952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700103/
https://www.ncbi.nlm.nih.gov/pubmed/36204852
http://dx.doi.org/10.4103/1673-5374.344952

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