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Poly-L-ornithine blocks the inhibitory effects of fibronectin on oligodendrocyte differentiation and promotes myelin repair

The extracellular matrix surrounding oligodendrocytes plays an important role during myelination and remyelination in the brain. In many cases, the microenvironment surrounding demyelination lesions contains inhibitory molecules, which lead to repair failure. Accordingly, blocking the activity of th...

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Detalles Bibliográficos
Autores principales: Xiong, Ya-Jie, Soomro, Shahid Hussain, Huang, Zhong-Hai, Yu, Pan-Pan, Ping, Jie, Fu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700116/
https://www.ncbi.nlm.nih.gov/pubmed/36204851
http://dx.doi.org/10.4103/1673-5374.353493