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Genotype-guided model significantly improves accuracy of tacrolimus initial dosing after liver transplantation
BACKGROUND: The initial dose of tacrolimus after liver transplantation (LT) is critical for rapidly achieving the steady state of the drug concentration, minimizing the potential adverse reactions and warranting long-term patient prognosis. We aimed to develop and validate a genotype-guided model fo...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700266/ https://www.ncbi.nlm.nih.gov/pubmed/36444212 http://dx.doi.org/10.1016/j.eclinm.2022.101752 |