Genotype-guided model significantly improves accuracy of tacrolimus initial dosing after liver transplantation

BACKGROUND: The initial dose of tacrolimus after liver transplantation (LT) is critical for rapidly achieving the steady state of the drug concentration, minimizing the potential adverse reactions and warranting long-term patient prognosis. We aimed to develop and validate a genotype-guided model fo...

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Detalles Bibliográficos
Autores principales: Shi, Baojie, Liu, Yuan, Liu, Dehua, Yuan, Liyun, Guo, Wenzhi, Wen, Peihao, Su, Zhaojie, Wang, Jie, Xu, Shiquan, Xia, Junjie, An, Wenbin, Wang, Rui, Wen, Peizhen, Xing, Tonghai, Zhang, Jinyan, Gu, Haitao, Wang, Zhaowen, Zhong, Lin, Fan, Junwei, Li, Hao, Zhang, Weituo, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700266/
https://www.ncbi.nlm.nih.gov/pubmed/36444212
http://dx.doi.org/10.1016/j.eclinm.2022.101752

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