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The impact of race, ethnicity, and obesity on CAR T-cell therapy outcomes

Cancer outcomes with chemotherapy are inferior in patients of minority racial/ethnic groups and those with obesity. Chimeric antigen receptor (CAR) T-cell therapy has transformed outcomes for relapsed/refractory hematologic malignancies, but whether its benefits extend commensurately to racial/ethni...

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Detalles Bibliográficos
Autores principales: Faruqi, Aiman J., Ligon, John A., Borgman, Paul, Steinberg, Seth M., Foley, Toni, Little, Lauren, Mackall, Crystal L., Lee, Daniel W., Fry, Terry J., Shalabi, Haneen, Brudno, Jennifer, Yates, Bonnie, Mikkilineni, Lekha, Kochenderfer, James, Shah, Nirali N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700270/
https://www.ncbi.nlm.nih.gov/pubmed/35939781
http://dx.doi.org/10.1182/bloodadvances.2022007676