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In silico predicted therapy against chronic Staphylococcus aureus infection leads to bacterial clearance in vivo

Staphylococcus aureus can lead to chronic infections and abscesses in internal organs including kidneys, which are associated with the expansion of myeloid-derived suppressor cells (MDSCs) and their suppressive effect on T cells. Here, we developed a mathematical model of chronic S. aureus infection...

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Detalles Bibliográficos
Autores principales: Papaxenopoulou, Lito A., Zhao, Gang, Khailaie, Sahamoddin, Katsoulis-Dimitriou, Konstantinos, Schmitz, Ingo, Medina, Eva, Hatzikirou, Haralampos, Meyer-Hermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700272/
https://www.ncbi.nlm.nih.gov/pubmed/36444298
http://dx.doi.org/10.1016/j.isci.2022.105522