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In silico predicted therapy against chronic Staphylococcus aureus infection leads to bacterial clearance in vivo
Staphylococcus aureus can lead to chronic infections and abscesses in internal organs including kidneys, which are associated with the expansion of myeloid-derived suppressor cells (MDSCs) and their suppressive effect on T cells. Here, we developed a mathematical model of chronic S. aureus infection...
Autores principales: | Papaxenopoulou, Lito A., Zhao, Gang, Khailaie, Sahamoddin, Katsoulis-Dimitriou, Konstantinos, Schmitz, Ingo, Medina, Eva, Hatzikirou, Haralampos, Meyer-Hermann, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700272/ https://www.ncbi.nlm.nih.gov/pubmed/36444298 http://dx.doi.org/10.1016/j.isci.2022.105522 |
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