OR04-6 Comprehensive Profiling of the MELK Inhibitor OTSSP167's Action and Its Effect on Sensitization to Wee1 Inhibitor AZD1775 in a Spectrum of ACC Models

Adrenocortical carcinoma (ACC) is an aggressive cancer with a significant risk of recurrence and high mortality rates. ACC has limited response to currently used treatments and there is an unmet clinical need to identify new treatment options. Disease rarity coupled with absence of preclinical model...

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Detalles Bibliográficos
Autores principales: Bagby, Stacey, Foust, Lindsey, Habra, Mouhammed Amir, Kiseljak-Vassiliades, Katja, Pitts, Todd, Pozdeyev, Nikita, Wierman, Margaret E, Kar, Adwitiya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Adrenal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700290/
http://dx.doi.org/10.1210/jendso/bvac150.170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700290/
http://dx.doi.org/10.1210/jendso/bvac150.170

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