Cargando…

Casting CRISPR-Cas13d to fish for microprotein functions in animal development

Protein coding genes were originally identified with sequence-based definitions that included a 100-codon cutoff to avoid annotating irrelevant open reading frames. However, many active proteins contain less than 100 amino acids. Indeed, functional genetics, ribosome profiling, and proteomic profili...

Descripción completa

Detalles Bibliográficos
Autores principales: Treichel, Anthony James, Bazzini, Ariel Alejandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700322/
https://www.ncbi.nlm.nih.gov/pubmed/36444300
http://dx.doi.org/10.1016/j.isci.2022.105547