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Casting CRISPR-Cas13d to fish for microprotein functions in animal development
Protein coding genes were originally identified with sequence-based definitions that included a 100-codon cutoff to avoid annotating irrelevant open reading frames. However, many active proteins contain less than 100 amino acids. Indeed, functional genetics, ribosome profiling, and proteomic profili...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700322/ https://www.ncbi.nlm.nih.gov/pubmed/36444300 http://dx.doi.org/10.1016/j.isci.2022.105547 |