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High-efficiency retron-mediated single-stranded DNA production in plants

Retrons are a class of retroelements that produce multicopy single-stranded DNA (ssDNA) and participate in anti-phage defenses in bacteria. Retrons have been harnessed for the overproduction of ssDNA, genome engineering and directed evolution in bacteria, yeast and mammalian cells. Retron-mediated s...

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Detalles Bibliográficos
Autores principales: Jiang, Wenjun, Sivakrishna Rao, Gundra, Aman, Rashid, Butt, Haroon, Kamel, Radwa, Sedeek, Khalid, Mahfouz, Magdy M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700382/
https://www.ncbi.nlm.nih.gov/pubmed/36452068
http://dx.doi.org/10.1093/synbio/ysac025