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Targeting fibroblast growth factor receptors causes severe craniofacial malformations in zebrafish larvae
BACKGROUND AND OBJECTIVE: A key pathway controlling skeletal development is fibroblast growth factor (FGF) and FGF receptor (FGFR) signaling. Major regulatory functions of FGF signaling are chondrogenesis, endochondral and intramembranous bone development. In this study we focus on fgfr2, as mutatio...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700454/ https://www.ncbi.nlm.nih.gov/pubmed/36444384 http://dx.doi.org/10.7717/peerj.14338 |