Dapagliflozin as an autophagic enhancer via LKB1/AMPK/SIRT1 pathway in ovariectomized/d-galactose Alzheimer’s rat model

Autophagy and mitochondrial deficits are characteristics of early phase of Alzheimer’s disease (AD). Sodium-glucose cotransporter-2 inhibitors have been nominated as a promising class against AD hallmarks. However, there are no available data yet to discuss the impact of gliflozins on autophagic pat...

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Detalles Bibliográficos
Autores principales: Ibrahim, Weam W., Kamel, Ahmed S., Wahid, Ahmed, Abdelkader, Noha F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700568/
https://www.ncbi.nlm.nih.gov/pubmed/35364737
http://dx.doi.org/10.1007/s10787-022-00973-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700568/
https://www.ncbi.nlm.nih.gov/pubmed/35364737
http://dx.doi.org/10.1007/s10787-022-00973-5

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