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Transcription factor NRF2 as potential therapeutic target for preventing muscle wasting in aging chronic kidney disease patients
Increased muscle protein catabolism leading to muscle wasting is a prominent feature of the syndrome of protein-energy wasting (PEW) in patients with chronic kidney disease (CKD). PEW and muscle wasting are induced by factors such as inflammation, oxidative stress and metabolic acidosis that activat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700608/ https://www.ncbi.nlm.nih.gov/pubmed/36322291 http://dx.doi.org/10.1007/s40620-022-01484-w |