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Transcription factor NRF2 as potential therapeutic target for preventing muscle wasting in aging chronic kidney disease patients

Increased muscle protein catabolism leading to muscle wasting is a prominent feature of the syndrome of protein-energy wasting (PEW) in patients with chronic kidney disease (CKD). PEW and muscle wasting are induced by factors such as inflammation, oxidative stress and metabolic acidosis that activat...

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Detalles Bibliográficos
Autores principales: Gómez-García, Erika F., del Campo, Fabiola Martín, Cortés-Sanabria, Laura, Mendoza-Carrera, Francisco, Avesani, Carla Maria, Stenvinkel, Peter, Lindholm, Bengt, Cueto-Manzano, Alfonso M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700608/
https://www.ncbi.nlm.nih.gov/pubmed/36322291
http://dx.doi.org/10.1007/s40620-022-01484-w