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Activin A and CCR2 regulate macrophage function in testicular fibrosis caused by experimental autoimmune orchitis
Experimental autoimmune-orchitis (EAO), a rodent model of chronic testicular inflammation and fibrosis, replicates pathogenic changes seen in some cases of human spermatogenic disturbances. During EAO, increased levels of pro-inflammatory and pro-fibrotic mediators such as TNF, CCL2, and activin A a...
Autores principales: | Peng, Wei, Kepsch, Artem, Kracht, Till O., Hasan, Hiba, Wijayarathna, Rukmali, Wahle, Eva, Pleuger, Christiane, Bhushan, Sudhanshu, Günther, Stefan, Kauerhof, A. Christine, Planinić, Ana, Fietz, Daniela, Schuppe, Hans-Christian, Wygrecka, Małgorzata, Loveland, Kate L., Ježek, Davor, Meinhardt, Andreas, Hedger, Mark P., Fijak, Monika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700630/ https://www.ncbi.nlm.nih.gov/pubmed/36434305 http://dx.doi.org/10.1007/s00018-022-04632-4 |
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