Nebivolol elicits a neuroprotective effect in the cuprizone model of multiple sclerosis in mice: emphasis on M1/M2 polarization and inhibition of NLRP3 inflammasome activation

BACKGROUND AND AIM: Multiple sclerosis (MS) is a demyelinating neurodegenerative inflammatory disease affecting mainly young adults. Microgliosis-derived neuroinflammation represents a key hallmark in MS pathology and progression. Nebivolol (Neb) demonstrated antioxidant, anti-inflammatory and neuro...

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Detalles Bibliográficos
Autores principales: Naeem, Antoinette G., El-Naga, Reem N., Michel, Haidy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700639/
https://www.ncbi.nlm.nih.gov/pubmed/35948811
http://dx.doi.org/10.1007/s10787-022-01045-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700639/
https://www.ncbi.nlm.nih.gov/pubmed/35948811
http://dx.doi.org/10.1007/s10787-022-01045-4

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