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A single-cell analysis reveals tumor heterogeneity and immune environment of acral melanoma

Acral melanoma is a dismal subtype of melanoma occurring in glabrous acral skin, and has a higher incidence in East Asians. We perform single-cell RNA sequencing for 63,394 cells obtained from 5 acral and 3 cutaneous melanoma samples to investigate tumor heterogeneity and immune environment. We defi...

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Detalles Bibliográficos
Autores principales: Zhang, Chao, Shen, Hongru, Yang, Tielong, Li, Ting, Liu, Xinyue, Wang, Jin, Liao, Zhichao, Wei, Junqiang, Lu, Jia, Liu, Haotian, Xiang, Lijie, Yang, Yichen, Yang, Meng, Wang, Duan, Li, Yang, Xing, Ruwei, Teng, Sheng, Zhao, Jun, Yang, Yun, Zhao, Gang, Chen, Kexin, Li, Xiangchun, Yang, Jilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700682/
https://www.ncbi.nlm.nih.gov/pubmed/36433984
http://dx.doi.org/10.1038/s41467-022-34877-3