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Hybrid chalcogen bonds in prodrug nanoassemblies provides dual redox-responsivity in the tumor microenvironment

Sulfur bonds, especially trisulfide bond, have been found to ameliorate the self-assembly stability of homodimeric prodrug nanoassemblies and could trigger the sensitive reduction-responsive release of active drugs. However, the antitumor efficacy of homodimeric prodrug nanoassemblies with single re...

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Detalles Bibliográficos
Autores principales: Liu, Tian, Li, Lingxiao, Wang, Shuo, Dong, Fudan, Zuo, Shiyi, Song, Jiaxuan, Wang, Xin, Lu, Qi, Wang, Helin, Zhang, Haotian, Cheng, Maosheng, Liu, Xiaohong, He, Zhonggui, Sun, Bingjun, Sun, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700694/
https://www.ncbi.nlm.nih.gov/pubmed/36434014
http://dx.doi.org/10.1038/s41467-022-35033-7