Cargando…
Hybrid chalcogen bonds in prodrug nanoassemblies provides dual redox-responsivity in the tumor microenvironment
Sulfur bonds, especially trisulfide bond, have been found to ameliorate the self-assembly stability of homodimeric prodrug nanoassemblies and could trigger the sensitive reduction-responsive release of active drugs. However, the antitumor efficacy of homodimeric prodrug nanoassemblies with single re...
Autores principales: | Liu, Tian, Li, Lingxiao, Wang, Shuo, Dong, Fudan, Zuo, Shiyi, Song, Jiaxuan, Wang, Xin, Lu, Qi, Wang, Helin, Zhang, Haotian, Cheng, Maosheng, Liu, Xiaohong, He, Zhonggui, Sun, Bingjun, Sun, Jin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700694/ https://www.ncbi.nlm.nih.gov/pubmed/36434014 http://dx.doi.org/10.1038/s41467-022-35033-7 |
Ejemplares similares
-
Small changes in the length of diselenide bond-containing linkages exert great influences on the antitumor activity of docetaxel homodimeric prodrug nanoassemblies
por: Li, Lingxiao, et al.
Publicado: (2021) -
Trisulfide bond–mediated doxorubicin dimeric prodrug nanoassemblies with high drug loading, high self-assembly stability, and high tumor selectivity
por: Yang, Yinxian, et al.
Publicado: (2020) -
Probing the fluorination effect on the self-assembly characteristics, in vivo fate and antitumor efficacy of paclitaxel prodrug nanoassemblies
por: Wang, Xin, et al.
Publicado: (2021) -
Impact of the amount of PEG on prodrug nanoassemblies for efficient cancer therapy
por: Li, Yaqiao, et al.
Publicado: (2022) -
Self-delivering prodrug-nanoassemblies fabricated by disulfide bond bridged oleate prodrug of docetaxel for breast cancer therapy
por: Zhang, Shenwu, et al.
Publicado: (2017)