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Valproic acid attenuates cellular senescence in diabetic kidney disease through the inhibition of complement C5a receptors

Despite increasing knowledge about the factors involved in the progression of diabetic complications, diabetic kidney disease (DKD) continues to be a major health burden. Current therapies only slow but do not prevent the progression of DKD. Thus, there is an urgent need to develop novel therapy to...

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Detalles Bibliográficos
Autores principales: Coughlan, Melinda T., Ziemann, Mark, Laskowski, Adrienne, Woodruff, Trent M., Tan, Sih Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700697/
https://www.ncbi.nlm.nih.gov/pubmed/36434087
http://dx.doi.org/10.1038/s41598-022-24851-w