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MYC and MET cooperatively drive hepatocellular carcinoma with distinct molecular traits and vulnerabilities
Enhanced activation of the transcription factor MYC and of the receptor tyrosine kinase MET are among the events frequently occurring in hepatocellular carcinoma (HCC). Both genes individually act as drivers of liver cancer initiation and progression. However, their concomitant alteration in HCC has...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700715/ https://www.ncbi.nlm.nih.gov/pubmed/36433941 http://dx.doi.org/10.1038/s41419-022-05411-6 |