Global landscape of replicative DNA polymerase usage in the human genome

The division of labour among DNA polymerase underlies the accuracy and efficiency of replication. However, the roles of replicative polymerases have not been directly established in human cells. We developed polymerase usage sequencing (Pu-seq) in HCT116 cells and mapped Polε and Polα usage genome w...

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Detalles Bibliográficos
Autores principales: Koyanagi, Eri, Kakimoto, Yoko, Minamisawa, Tamiko, Yoshifuji, Fumiya, Natsume, Toyoaki, Higashitani, Atsushi, Ogi, Tomoo, Carr, Antony M., Kanemaki, Masato T., Daigaku, Yasukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700718/
https://www.ncbi.nlm.nih.gov/pubmed/36434012
http://dx.doi.org/10.1038/s41467-022-34929-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700718/
https://www.ncbi.nlm.nih.gov/pubmed/36434012
http://dx.doi.org/10.1038/s41467-022-34929-8

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