Cargando…

Global landscape of replicative DNA polymerase usage in the human genome

The division of labour among DNA polymerase underlies the accuracy and efficiency of replication. However, the roles of replicative polymerases have not been directly established in human cells. We developed polymerase usage sequencing (Pu-seq) in HCT116 cells and mapped Polε and Polα usage genome w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koyanagi, Eri, Kakimoto, Yoko, Minamisawa, Tamiko, Yoshifuji, Fumiya, Natsume, Toyoaki, Higashitani, Atsushi, Ogi, Tomoo, Carr, Antony M., Kanemaki, Masato T., Daigaku, Yasukazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700718/ https://www.ncbi.nlm.nih.gov/pubmed/36434012 http://dx.doi.org/10.1038/s41467-022-34929-8

Ejemplares similares

A global profile of replicative polymerase usage
por: Daigaku, Yasukazu, et al.
Publicado: (2015)

Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity
por: Eaton, Joshua D., et al.
Publicado: (2018)

PCNA ubiquitylation ensures timely completion of unperturbed DNA replication in fission yeast
por: Daigaku, Yasukazu, et al.
Publicado: (2017)

Dynein–Dynactin–NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
por: Okumura, Masako, et al.
Publicado: (2018)

Chromosome oscillation promotes Aurora A–dependent Hec1 phosphorylation and mitotic fidelity
por: Iemura, Kenji, et al.
Publicado: (2021)

Polymerase δ replicates both strands after homologous recombination-dependent fork restart
por: Miyabe, Izumi, et al.
Publicado: (2015)

Acute inactivation of the replicative helicase in human cells triggers MCM8–9-dependent DNA synthesis
por: Natsume, Toyoaki, et al.
Publicado: (2017)

Inhibiting the MCM8‐9 complex selectively sensitizes cancer cells to cisplatin and olaparib
por: Morii, Issay, et al.
Publicado: (2019)

Optimisation of the Schizosaccharomyces pombe urg1 Expression System
por: Watson, Adam T., et al.
Publicado: (2013)

The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress
por: Watts, Lotte P, et al.
Publicado: (2020)

Motif programming: a microgene-based method for creating synthetic proteins containing multiple functional motifs
por: Saito, Hirohide, et al.
Publicado: (2007)

Auxin-inducible protein depletion system in fission yeast
por: Kanke, Mai, et al.
Publicado: (2011)

Ubiquitin-dependent DNA damage bypass is separable from genome replication
por: Daigaku, Yasukazu, et al.
Publicado: (2010)

Genome Landscapes and Bacteriophage Codon Usage
por: Lucks, Julius B., et al.
Publicado: (2008)

TRAIP resolves DNA replication-transcription conflicts during the S-phase of unperturbed cells
por: Scaramuzza, Shaun, et al.
Publicado: (2023)

Condensins Promote Chromosome Recoiling during Early Anaphase to Complete Sister Chromatid Separation
por: Renshaw, Matthew J., et al.
Publicado: (2010)

The dimeric Mcm8–9 complex of Xenopus laevis likely has a conserved function for resistance to DNA damage
por: Kanemaki, Masato T.
Publicado: (2013)

A DNA Polymerase α Accessory Protein, Mcl1, Is Required for Propagation of Centromere Structures in Fission Yeast
por: Natsume, Toyoaki, et al.
Publicado: (2008)

Mitotic DNA synthesis in response to replication stress requires the sequential action of DNA polymerases zeta and delta in human cells
por: Wu, Wei, et al.
Publicado: (2023)

Isolation of human salivary extracellular vesicles by iodixanol density gradient ultracentrifugation and their characterizations
por: Iwai, Kazuya, et al.
Publicado: (2016)

Activation of Ubiquitin-Dependent DNA Damage Bypass Is Mediated by Replication Protein A
por: Davies, Adelina A., et al.
Publicado: (2008)

The ubiquitination landscape of the influenza A virus polymerase
por: Günl, Franziska, et al.
Publicado: (2023)

RNA ligands activate the Machupo virus polymerase and guide promoter usage
por: Pyle, Jesse D., et al.
Publicado: (2019)

Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage
por: Espah Borujeni, Amin, et al.
Publicado: (2020)

The assembly of the MCM2–7 hetero-hexamer and its significance in DNA replication
por: Hatoyama, Yuki, et al.
Publicado: (2023)

Spatial regulation and organization of DNA replication within the nucleus
por: Natsume, Toyoaki, et al.
Publicado: (2009)

Spatial separation between replisome‐ and template‐induced replication stress signaling
por: García‐Rodríguez, Néstor, et al.
Publicado: (2018)

Usage statistics and demonstrator services
por: Carr, Leslie
Publicado: (2007)

SETDB1, HP1 and SUV39 promote repositioning of 53BP1 to extend resection during homologous recombination in G2 cells
por: Alagoz, Meryem, et al.
Publicado: (2015)

Encryption of agonistic motifs for TLR4 into artificial antigens augmented the maturation of antigen-presenting cells
por: Ito, Masaki, et al.
Publicado: (2017)

The Major Roles of DNA Polymerases Epsilon and Delta at the Eukaryotic Replication Fork Are Evolutionarily Conserved
por: Miyabe, Izumi, et al.
Publicado: (2011)

Cryo-EM structures of human SPCA1a reveal the mechanism of Ca(2+)/Mn(2+) transport into the Golgi apparatus
por: Chen, Zhenghao, et al.
Publicado: (2023)

Single nucleosome imaging reveals loose genome chromatin networks via active RNA polymerase II
por: Nagashima, Ryosuke, et al.
Publicado: (2019)

Usage statistics and demonstrator services
por: Carr, Leslie, et al.
Publicado: (2007)

Constructing Auxin-Inducible Degron Mutants Using an All-in-One Vector
por: Yesbolatova, Aisha, et al.
Publicado: (2020)

Three wise centromere functions: see no error, hear no break, speak no delay
por: Tanaka, Tomoyuki U, et al.
Publicado: (2013)

Combinatorial Contextualization of Peptidic Epitopes for Enhanced Cellular Immunity
por: Ito, Masaki, et al.
Publicado: (2014)

Anesthetic management in a patient with severe tracheal stenosis by monitoring oxygen reserve index
por: Matsuba, Sho, et al.
Publicado: (2022)

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy
por: Etheridge, Thomas J., et al.
Publicado: (2014)

Technical approaches to citations and usage analysis
por: Scholze, Frank, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_nel1mnmetp5epa82jkg7abj192