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PICH acts as a force-dependent nucleosome remodeler

In anaphase, any unresolved DNA entanglements between the segregating sister chromatids can give rise to chromatin bridges. To prevent genome instability, chromatin bridges must be resolved prior to cytokinesis. The SNF2 protein PICH has been proposed to play a direct role in this process through th...

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Detalles Bibliográficos
Autores principales: Spakman, Dian, Clement, Tinka V. M., Biebricher, Andreas S., King, Graeme A., Singh, Manika I., Hickson, Ian D., Peterman, Erwin J. G., Wuite, Gijs J. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700735/
https://www.ncbi.nlm.nih.gov/pubmed/36433994
http://dx.doi.org/10.1038/s41467-022-35040-8