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Mesenchymal stem/stromal cells primed by inflammatory cytokines alleviate psoriasis-like inflammation via the TSG-6-neutrophil axis

Psoriasis is currently an incurable skin disorder mainly driven by a chronic inflammatory response. We found that subcutaneous application of umbilical cord- derived mesenchymal stem/stromal cells (MSCs) primed by IFN-γ and TNF-α, referred to as MSCs-IT, exhibited remarkable therapeutic efficacy on...

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Detalles Bibliográficos
Autores principales: Ding, Yayun, Gong, Pixia, Jiang, Junjie, Feng, Chao, Li, Yanan, Su, Xiao, Bai, Xiaojing, Xu, Chenchang, Liu, Chunxiao, Yang, Jianxin, Fang, Jiankai, Ji, Xiaocao, Chen, Yongjing, Li, Peishan, Guo, Lingchuan, Shao, Changshun, Shi, Yufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700741/
https://www.ncbi.nlm.nih.gov/pubmed/36433947
http://dx.doi.org/10.1038/s41419-022-05445-w