Rac1 deficiency impairs postnatal development of the renal papilla

Development of the renal medulla continues after birth to form mature renal papilla and obtain urine-concentrating ability. Here, we found that a small GTPase, Rac1, plays a critical role in the postnatal development of renal papilla. Mice with distal tubule-specific deletion of Rac1 reached adultho...

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Detalles Bibliográficos
Autores principales: Ayuzawa, Nobuhiro, Nishimoto, Mitsuhiro, Kawarazaki, Wakako, Oba, Shigeyoshi, Marumo, Takeshi, Aiba, Atsu, Fujita, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700760/
https://www.ncbi.nlm.nih.gov/pubmed/36434091
http://dx.doi.org/10.1038/s41598-022-24462-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700760/
https://www.ncbi.nlm.nih.gov/pubmed/36434091
http://dx.doi.org/10.1038/s41598-022-24462-5

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