A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation

Strategies to prevent the recurrence of poliovirus (PV) after eradication may utilise non-infectious, recombinant virus-like particle (VLP) vaccines. Despite clear advantages over inactivated or attenuated virus vaccines, instability of VLPs can compromise their immunogenicity. Glutathione (GSH), an...

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Detalles Bibliográficos
Autores principales: Bahar, Mohammad W., Nasta, Veronica, Fox, Helen, Sherry, Lee, Grehan, Keith, Porta, Claudine, Macadam, Andrew J., Stonehouse, Nicola J., Rowlands, David J., Fry, Elizabeth E., Stuart, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700776/
https://www.ncbi.nlm.nih.gov/pubmed/36434067
http://dx.doi.org/10.1038/s42003-022-04252-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700776/
https://www.ncbi.nlm.nih.gov/pubmed/36434067
http://dx.doi.org/10.1038/s42003-022-04252-5

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