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KBTBD11, encoding a novel PPARγ target gene, is involved in NFATc1 proteolysis by interacting with HSC70 and HSP60

We previously revealed that Kbtbd11 mRNA levels increase during 3T3-L1 differentiation and Kbtbd11 knockdown suppresses whereas its overexpression promotes adipogenesis. However, how Kbtbd11 mRNA is regulated during adipocyte differentiation and how the KBTBD11 protein functions in adipocytes remain...

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Detalles Bibliográficos
Autores principales: Watanabe, Kazuhisa, Matsumoto, Ayumi, Tsuda, Hidetoshi, Iwamoto, Sadahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700792/
https://www.ncbi.nlm.nih.gov/pubmed/36434268
http://dx.doi.org/10.1038/s41598-022-24929-5