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Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4(+) regulatory T cells

The CD4(+) regulatory T (Treg) cell lineage, defined by FOXP3 expression, comprises thymus-derived (t)Treg cells and peripherally induced (p)Treg cells. As a model for Treg cells, studies employ TGF-β-induced (i)Treg cells generated from CD4(+) conventional T (Tconv) cells in vitro. Here, we describ...

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Detalles Bibliográficos
Autores principales: Mensink, Mark, Schrama, Ellen, Cuadrado, Eloy, Amsen, Derk, de Kivit, Sander, Borst, Jannie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700829/
https://www.ncbi.nlm.nih.gov/pubmed/36434024
http://dx.doi.org/10.1038/s41598-022-23515-z