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Promotion effect of apical tooth germ cell-conditioned medium on osteoblastic differentiation of periodontal ligament stem cells through regulating miR-146a-5p

BACKGROUND: MicroRNAs (miRNAs) play an important role in gene regulation that controls stem cells differentiation. Periodontal ligament stem cells (PDLSCs) could differentiate into osteo-/cementoblast-like cells that secretes cementum-like matrix both in vitro and in vivo. Whether miRNAs play key ro...

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Detalles Bibliográficos
Autores principales: Xie, Yueqiang, Zheng, Yaxin, Chen, Liangjiao, Lan, Zedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700872/
https://www.ncbi.nlm.nih.gov/pubmed/36434576
http://dx.doi.org/10.1186/s12903-022-02485-8