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Upregulation of Ca(2+)-binding proteins contributes to VTA dopamine neuron survival in the early phases of Alzheimer’s disease in Tg2576 mice

BACKGROUND: Recent clinical and experimental studies have highlighted the involvement of Ventral Tegmental Area (VTA) dopamine (DA) neurons for the early pathogenesis of Alzheimer’s Disease (AD). We have previously described a progressive and selective degeneration of these neurons in the Tg2576 mou...

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Detalles Bibliográficos
Autores principales: La Barbera, Livia, Nobili, Annalisa, Cauzzi, Emma, Paoletti, Ilaria, Federici, Mauro, Saba, Luana, Giacomet, Cecilia, Marino, Ramona, Krashia, Paraskevi, Melone, Marcello, Keller, Flavio, Mercuri, Nicola Biagio, Viscomi, Maria Teresa, Conti, Fiorenzo, D’Amelio, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700939/
https://www.ncbi.nlm.nih.gov/pubmed/36434727
http://dx.doi.org/10.1186/s13024-022-00580-6