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TALASUR trial: a single arm phase II trial assessing efficacy and safety of TALazoparib and Avelumab as maintenance therapy in platinum-Sensitive metastatic or locally advanced URothelial carcinoma

BACKGROUND: Urothelial carcinoma (UC) is the ninth most commonly diagnosed cancer worldwide, with a 3.8/1 male to female ratio. Platinum-based chemotherapy is the first line standard of care for fit patients with advanced UC. However, despite a response rate (RR) for approximately half of patients r...

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Detalles Bibliográficos
Autores principales: Coquan, Elodie, Clarisse, Bénédicte, Lequesne, Justine, Brachet, Pierre-Emmanuel, Nevière, Zoé, Meriaux, Emeline, Bonnet, Isabelle, Castera, Marie, Goardon, Nicolas, Boutrois, Jeremy, Travers, Romain, Joly, Florence, Grellard, Jean-Michel, Thiery-Vuillemin, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9700963/
https://www.ncbi.nlm.nih.gov/pubmed/36434554
http://dx.doi.org/10.1186/s12885-022-10216-z